If you want to flag a grid as read-only, so that it cannot be altered or re-interpolated, specify "READ ONLY": "T" for the parameter name : parameter value pair, which can be passed with either MapInfo Pro TIN or IDW interpolators. If this parameter value is used, then the metadata tag:
"\Interpolator\Parameter\READ ONLY" = "0"
is written into the TAB file and the user will not be able to modify or re-interpolate the grid via the user interface.